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Hexidine Scrub

PRESENTATION:

Hexidine®  Scrub: A clean, dark red solution free from visible evidence of contamination with a characteristic odour. It contains: Chlorhexidine Gluconate 4%w/v equivalent to 20% v/v Chlorhexidine Gluconate Solution BP.

CLINICAL  PHARMACOLOGY:

Chlorhexidine  is a bisbiguanide antiseptic and disinfectant which is bactericidal or bacteriostatic against a wide range of Gram-positive and Gram-negative bacteria. It exerts its lethal effects upon bacterial cells through non-specific interaction with acidic phospholipids of the cell membranes . Such interaction alters the permeability of the cell membranes towards small inorganic materials such as potassium and towards cytosolic constituents such as aminoacids and nucleotides. The functioning of membrane-associated enzymes such as the dehydrogenases and ATPase is indirectly affected through such membrane action.

PHARMACOKINETICS:

Chlorhexidine is poorly absorbed from the gastro-intestinal tract and skin.

USES:

Hexidine® Scrub is effective against a wide range of Gram-negative and Gram-positive vegetative bacteria, yeasts, dermatophytic fungi and lipophilic viruses.

INSTRUCTIONS  FOR  USE:

Antiseptic hand-washing.
Apply 5mL Chlorhexidine Gluconate Solution and wash for one minute paying special attention to finger nails. Rinse thoroughly and dry well.
Pre-operative surgical hand-disinfection.
Apply 5mL Chlorhexidine Gluconate Solution. Wash for one minute. Clean the finger nails with a brush or a scrapper. Rinse thoroughly and dry well. Repeat the wash with a further 5mL for 2 minutes. Rinse thoroughly and dry well.

FOR EXTERNAL USE ONLY

CONTRA-INDICATIONS  AND  WARNINGS:


Hexidine®  Scrub is contra- indicated for patients who have previously shown  hypersensitivity reactions to chlorhexidine. However such reactions are extremely rare. Avoid contact with the brain meninges and middle ear. Not for injection. Do not use in the body cavities.
The concentrated solution is irritant to eyes and mucous membranes. Keep all solutions out of the eyes. If solutions do come into contact with the eyes , wash out promptly with water.
Prolonged skin contact with alcoholic solution should be avoided. Allow to dry before proceeding.
Solutions applied to wounds, burns or broken skin should be sterile. Syringes, needles and instruments which have been immersed in Hexidine solution should be thoroughly rinsed in sterile water or saline before use.

Adverse Effects:


Irritative skin reactions can occasionally occur. Generalised allergic reactions to Chlorhexidine have also been reported but are extremely rare.
Accidental Ingestion:
Chlorhexidine taken orally is poorly absorbed. Treat with gastric lavage using milk, raw egg, gelatin or mild soap. Employ supportive measures as appropriate.
Accidental Intravenous Infusion:
Blood  transfusion may be necessary to counteract haemolysis.

PHARMACEUTICAL PRECAUTIONS:

Store in cool dry place, Protect from light. Keep out of reach of children.

LEGAL CATEGORY:
General Sales List (GSL)
Over The Counter (OTC)
®Regd. TM                   Ref. No: INS212/11.02

Quantity:
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